DNA nanoswitches find new drug leads faster by measuring protein interactions
Nov 05, 2026
Researchers at the Wyss Institute at Harvard University, Boston Children's Hospital, and Harvard Medical School (HMS) have developed FIND, a drug discovery platform that searches large libraries for molecules that modulate binding interactions between two proteins. FIND uses DNA nanoswitches to sele
ct drug candidates based on their effects on these protein-protein interactions, rather than simply whether they bind to a single target protein, giving it a key advantage over conventional binding-based screening. ...read more read less