(KRON) -- On the same day the Trump Administration unceremoniously shut down the U.S. Department of Health and Human Services Regional Office in San Francisco, a major HIV drug maker announced it would be cutting nearly 150 Bay Area jobs. Gilead Sciences, which is headquartered in Foster City on the Peninsula, will be laying off 149 people, according to a filing with the Employment Development Department. The cuts at Gilead, which in addition to HIV medicines, develops treatments for liver disease, cancer, and inflammatory conditions, come on the heels to mass job cuts at the HHS SF regional office. The office, which is located in the Speaker Nancy Pelosi Federal Building, was home to the Ryan White HIV/AIDS program. ‘It feels intentionally cruel’: DHHS employees address April Fool’s Day layoffs Gilead has been in the process of rolling out lenacapavir, a twice-yearly set of injections intended to provide virtually full protection against HIV infection, a form or treatment known as pre-exposure prophylaxis (PrEP). There has been speculation that federal budget cuts in the Trump administration lead by Elon Musk, the un-elected and unofficial head of the Department of Government Efficiency (DOGE), could potentially impact HIV drugs, leading to a drop in Gilead share prices last month. However, according to the San Francisco Business Times, Gilead Science's CEO Dan O'Day received a 5% pay increase last year, seeing his pay package rise from $22.6 million to $23.7 million. This is the second round of significant layoffs Gilead has announced in the last six months. In November, the company cut 104 jobs at its Foster City headquarters. Those job cuts, according to a state filing, took effect last month. The latest Gilead layoffs are set to take effect at the end of May, according to the state filing. ...read more read less