Human 'domainome' reveals root cause of heritable disease

Jan 08, 2025

Unstable proteins are the main drivers of many different heritable diseases, according to a new study, including genetic disorders responsible for the formation of cataracts, and different types of rare neurological, developmental and muscle-wasting diseases. Unstable proteins are more likely to misfold and degrade, causing them to stop working or accumulate in harmful amounts inside cells.