Staphylococcus aureus thwarts vaccines by turning on a protein that halts immune response

Dec 16, 2024

After dozens of clinical trials, there are still no effective vaccines against Staphylococcus aureus. In two new studies, scientists report that the pathogen turns on the protein interleukin 10, shutting down the protective vaccine response. But blocking the protein restores vaccine efficacy in an animal model.