Photo by Scott W. Grau/Icon Sportswire via Getty Images How to watch Lions vs. Bills: TV channel options, streaming, radio, and more. With only four weeks left in the 2024 NFL regular season, there aren’t going to be many more matchups as high-profile as this Week 15 game in Ford Field. The 12-1 Detroit Lions are hosting the 10-3 Buffalo Bills. Many consider these teams to be the favorites to win their respective conferences. The Lions are Vegas’ choice to represent the NFC (+145, per FanDuel), while the Bills’ odds to win the AFC (+250) are only behind the back-to-back Super Bowl champion Kansas City Chiefs (+175). While this game isn’t exactly getting the nationally-televised treatment, it is CBS’ game of the week. In fact, their pre-game show will be set up right outside of Ford Field this week: NFL ON CBS: WEEK 15 RUNDOWNJared Goff and the Lions host Josh Allen and the Bills in a battle of two of the NFL's top teams at 4:25 PM ETTHE NFL TODAY takes the show on the road, live from Detroit at Noon ET pic.twitter.com/1MZNBq0qoj— CBS Sports PR (@CBSSportsGang) December 12, 2024 CBS is also sending their No. 1 broadcasting crew—featuring announcers Jim Nantz and Tony Romo—to the game. So if you’re watching from home, expect a well-called game (unless Romo annoys you—which.... fair). You’ll also have local and national radio options if you prefer to consume game audio that way. Here’s all the ways you can catch the marquee Week 15 matchup between the Lions and Bills. Week 15: Buffalo Bills at Detroit Lions Date: Sunday, December 15, 2024Time: 4:25 p.m. ETLocation: Ford Field — Detroit, MITV: CBSTV map: Courtesy of 506 Sports Online streaming: NFL+, YouTube TVTV announcers: Jim Nantz, Tony Romo, Tracy WolfsonLocal radio: 97.1 The Ticket (full list of radio affiliates here)Radio announcers: Dan Miller, Lomas Brown, T.J. LangNational radio: Sports USANational radio announcers: Larry Kahn, James WhiteBetting line: Lions by 2.5, per FanDuel