Most major retailers are closed on Thursday, and several grocery and pharmacy chains also remain closed. Here is a look at what is open and what's not this Thanksgiving. Note that hours may vary, and many locations will have adjusted hours. Also, chains that are franchised-owned restaurants, like Subway and Burger King, will depend on the franchisee.What's open: Applebee's CVS H-E-B (7 a.m. to 12 p.m.) Denny's Dunkin' Guerra's Restaurant Ol' Steakhouse Boardwalk Cafe Aloha Pacific Island Grill IHOP Whataburger Bien Mrit Landrys Seafood House Starbucks Saltgrass Steakhouse  Luby's The Astor Chops & Eggs Pic-A-Dilly Big Lot's Firestone Vans Snoopy's Pier Thai Spice U&I Steakhouse Bluffalo Wings Co. Omni Hotel Cracker Barrel Walgreens (note, only about 500 24-hour locations will open; the rest will remain closed)Also, essential government offices, such as the National Weather Service, Transportation Security Administration, and others, willWhat's closed: Banks Best Buy Dominos Most government offices Pizza Hut Stock markets Target Walmart TJ Maxx Marshall's HomeGoods Kohl's Home Depot Lowe's Sephora La Palmera Macys Bath & Body Works Buckle GameStop Hollister PINK Ulta Aeropostale McDonald's Rock Star Sushi & Hibachi Most Walgreens locations