The Cleveland Cavaliers and Boston Celtics will face off at TD Garden tonight at 7 p.m. EST. Featuring the top two teams in the NBA’s Eastern Conference, this heavyweight matchup also includes some of the sport’s brightest, including the Cavs’ Donovan Mitchell and the Celtics’ Jayson Tatum. While Cleveland has started the season with 15 consecutive victories — the second-best start to an NBA season in league history — our data model believes the defending champion Celtics will be the ones to hand the Cavs their first defeat. Our best bet is Celtics moneyline (-190).