Comedy film duos have a long history, from Laurel and Hardy in the 1920s and ‘30s to Tina Fey and Amy Poehler in movies like Baby Mama. But the majority of duos have either been friends or work partners; relationships that can be close, but not as close as family. The new film A Real Pain aims for the comedy that a great duo can bring, but hits deeper because the two lead characters are related to each other.