OMRF studies why some older people benefit from exercise more than others
Nov 05, 2024
OKLAHOMA CITY (KFOR) - Exercise has always been fundamental to maintaining overall health, especially as you age. Some older people can benefit from certain workouts more than others.
The Oklahoma Medical Research Foundation is partnering with the University of Florida and Florida Institute for Human and Machine Cognition to find out why that’s the case.
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Everything from strength training to resistance training and some of it will take place inside the OMRF’s fitness center to determine certain responses to certain workouts and cardiovascular health.
A $7.7 million grant was given for the study that won’t be a sprint, but instead a 5 year marathon.
"It's important and to stay as physically active as you can,” Sue Bodine, Ph.D. and professor at the OMRF said.
Bodine and Benjamin Miller, Ph.D. will be the two scientists at the OMRF partaking in the study. She said the plan is to recruit roughly 200 people aged 60 and older who don’t exercise regularly.
"They will come in and get a number of clinical parameters measured, and then they will start a 12 week exercise study,” Bodine said.
After 12 weeks, they’ll see if there’s improvement in cardiorespiratory fitness and muscle strength. Then comes a second phase where workout intensity increases for those who showed no gains in phase one.
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"To see if we can tweak the exercise protocol so that they respond,” Bodine said.
Samples of blood and muscle biopsies as well as metabolism and body composition will be looked at as potential predictors of response. It may not be fully known why they do or don’t, but if Bodine and her colleagues can find out why, it can change the future.
"The end goal would be personalized medicine,” Bodine said. “To see if you can you personalize the exercise prescription so that people will respond and have better health outcomes."
In the second phase they also plan to monitor sleep and diet. They plan to start recruiting after the first of next year.