Based on our projections, the best bet versus the spread in the NFL among Week 7’s 15 matchups is Chiefs +1.5 — for more tips, including parlay opportunities, scroll down. Find an edge on the competition and take advantage of our spread picks for the NFL. BetMGM has all the information you need to start wagering on the NFL. NFL Picks Against the Spread – Week 7 Jump to Matchup: KC-SF | NYJ-PIT | DEN-NO | HOU-GB | DET-MIN | PHI-NYG | SEA-ATL | LAC-ARI | MIA-IND | BAL-TB | NE-JAX | CIN-CLE | LV-LAR | CAR-WAS | TEN-BUF Pick: Chiefs +1.5 vs. 49ers Matchup: Kansas City Chiefs at San Francisco 49ers Projected Winner & Margin: Chiefs by 7.6 points (Bet on this game at BetMGM) Spread: 49ers -1.5 Time: 4:25 p.m. ET Date: Oct. 20 TV Channel: FOX Live Stream: Watch this game on Fubo (Regional restrictions may apply) Pick: Steelers +1.5 vs. Jets Matchup: New York Jets at Pittsburgh Steelers Projected Winner & Margin: Steelers by 10.1 points (Bet on this game at BetMGM) Spread: Jets -1.5 Time: 8:20 p.m. ET Date: Oct. 20 TV Channel: NBC Live Stream: Watch this game on Fubo (Regional restrictions may apply) Pick: Saints +2.5 vs. Broncos Matchup: Denver Broncos at New Orleans Saints Projected Winner & Margin: Saints by 0.2 points (Bet on this game at BetMGM) Spread: Broncos -2.5 Time: 8:15 p.m. ET Date: Oct. 17 TV Channel: Amazon Prime Video Live Stream: Watch this game on Prime Video (Regional restrictions may apply) Pick: Packers -2.5 vs. Texans Matchup: Houston Texans at Green Bay Packers Projected Winner & Margin: Packers by 6.7 points (Bet on this game at BetMGM) Spread: Packers -2.5 Time: 1 p.m. ET Date: Oct. 20 TV Channel: CBS Live Stream: Paramount+ | Fubo (Regional restrictions may apply) Pick: Vikings -2.5 vs. Lions Matchup: Detroit Lions at Minnesota Vikings Projected Winner & Margin: Vikings by 10.8 points (Bet on this game at BetMGM) Spread: Vikings -2.5 Time: 1 p.m. ET Date: Oct. 20 TV Channel: FOX Live Stream: Watch this game on Fubo (Regional restrictions may apply) Pick: Eagles -3 vs. Giants Matchup: Philadelphia Eagles at New York Giants Projected Winner & Margin: Eagles by 6.6 points (Bet on this game at BetMGM) Spread: Eagles -3 Time: 1 p.m. ET Date: Oct. 20 TV Channel: FOX Live Stream: Watch this game on Fubo (Regional restrictions may apply) Pick: Falcons -3 vs. Seahawks Matchup: Seattle Seahawks at Atlanta Falcons Projected Winner & Margin: Falcons by 13.5 points (Bet on this game at BetMGM) Spread: Falcons -3 Time: 1 p.m. ET Date: Oct. 20 TV Channel: FOX Live Stream: Watch this game on Fubo (Regional restrictions may apply) Pick: Chargers -3 vs. Cardinals Matchup: Los Angeles Chargers at Arizona Cardinals Projected Winner & Margin: Chargers by 3.6 points (Bet on this game at BetMGM) Spread: Chargers -3 Time: 9 p.m. ET Date: Oct. 21 TV Channel: ESPN+ Live Stream: Pick: Colts -3.5 vs. Dolphins Matchup: Miami Dolphins at Indianapolis Colts Projected Winner & Margin: Colts by 19.6 points (Bet on this game at BetMGM) Spread: Colts -3.5 Time: 1 p.m. ET Date: Oct. 20 TV Channel: FOX Live Stream: Watch this game on Fubo (Regional restrictions may apply) Pick: Buccaneers +3.5 vs. Ravens Matchup: Baltimore Ravens at Tampa Bay Buccaneers Projected Winner & Margin: Buccaneers by 11.1 points (Bet on this game at BetMGM) Spread: Ravens -3.5 Time: 8:15 p.m. ET Date: Oct. 21 TV Channel: ESPN Live Stream: Watch this game on Fubo (Regional restrictions may apply) Pick: Patriots +5.5 vs. Jaguars Matchup: New England Patriots vs. Jacksonville Jaguars Projected Winner & Margin: Jaguars by 0.5 points (Bet on this game at BetMGM) Spread: Jaguars -5.5 Time: 9:30 a.m. ET Date: Oct. 20 TV Channel: NFL Network Live Stream: Watch this game on Fubo (Regional restrictions may apply) Pick: Bengals -6.5 vs. Browns Matchup: Cincinnati Bengals at Cleveland Browns Projected Winner & Margin: Bengals by 6.6 points (Bet on this game at BetMGM) Spread: Bengals -6.5 Time: 1 p.m. ET Date: Oct. 20 TV Channel: CBS Live Stream: Paramount+ | Fubo (Regional restrictions may apply) Pick: Rams -6.5 vs. Raiders Matchup: Las Vegas Raiders at Los Angeles Rams Projected Winner & Margin: Rams by 9.7 points (Bet on this game at BetMGM) Spread: Rams -6.5 Time: 4:05 p.m. ET Date: Oct. 20 TV Channel: CBS Live Stream: Paramount+ | Fubo (Regional restrictions may apply) Pick: Commanders -7.5 vs. Panthers Matchup: Carolina Panthers at Washington Commanders Projected Winner & Margin: Commanders by 24.7 points (Bet on this game at BetMGM) Spread: Commanders -7.5 Time: 4:05 p.m. ET Date: Oct. 20 TV Channel: CBS Live Stream: Paramount+ | Fubo (Regional restrictions may apply) Pick: Bills -9 vs. Titans Matchup: Tennessee Titans at Buffalo Bills Projected Winner & Margin: Bills by 12.5 points (Bet on this game at BetMGM) Spread: Bills -9 Time: 1 p.m. ET Date: Oct. 20 TV Channel: CBS Live Stream: Paramount+ | Fubo (Regional restrictions may apply) Catch every NFL touchdown with NFL RedZone on Fubo. 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