What’s the best bet to make, looking at each of the 14 matchups on the NFL’s Week 6 schedule? Our favorite point-spread choice is Eagles -8.5, but we have lots more suggestions for you, which could lead to parlay opportunities, below. Take advantage of our predictions to make your NFL picks this week. BetMGM has all the information you need to begin betting on the NFL. Best Week 6 Spread Bets Jump to Matchup: IND-TEN | JAX-CHI | BUF-NYJ | LAC-DEN | PIT-LV Pick: Titans +1 vs. Colts Matchup: Indianapolis Colts at Tennessee Titans Projected Winner & Margin: Colts by 0.6 points (Bet on this game at BetMGM) Spread: Colts -1 Time: 1:00 p.m. ET Date: Oct. 13 TV Channel: CBS Live Stream: Paramount+ | Fubo (Regional restrictions may apply) Pick: Bears -2.5 vs. Jaguars Matchup: Jacksonville Jaguars vs. Chicago Bears Projected Winner & Margin: Bears by 13.5 points (Bet on this game at BetMGM) Spread: Bears -2.5 Time: 9:30 a.m. ET Date: Oct. 13 TV Channel: NFL Network Live Stream: Watch this game on Fubo (Regional restrictions may apply) Pick: Jets +2.5 vs. Bills Matchup: Buffalo Bills at New York Jets Projected Winner & Margin: Jets by 3.2 points (Bet on this game at BetMGM) Spread: Bills -2.5 Time: 8:15 p.m. ET Date: Oct. 14 TV Channel: ESPN Live Stream: Watch this game on Fubo (Regional restrictions may apply) Pick: Broncos +3 vs. Chargers Matchup: Los Angeles Chargers at Denver Broncos Projected Winner & Margin: Broncos by 6.4 points (Bet on this game at BetMGM) Spread: Chargers -3 Time: 4:05 p.m. ET Date: Oct. 13 TV Channel: CBS Live Stream: Paramount+ | Fubo (Regional restrictions may apply) Pick: Steelers -3 vs. Raiders Matchup: Pittsburgh Steelers at Las Vegas Raiders Projected Winner & Margin: Steelers by 8.7 points (Bet on this game at BetMGM) Spread: Steelers -3 Time: 4:05 p.m. ET Date: Oct. 13 TV Channel: CBS Live Stream: Paramount+ | Fubo (Regional restrictions may apply) Make smart decisions. Use those stats when making your NFL picks and place your bet on BetMGM. Best Week 6 Total Bets Jump to Matchup: TB-NO | WAS-BAL | LAC-DEN | ARI-GB | DET-DAL Over 41.5 – Buccaneers vs. Saints Matchup: Tampa Bay Buccaneers at New Orleans Saints Projected Total: 47.7 points (Bet on this game at BetMGM) Time: 1:00 p.m. ET Date: Oct. 13 TV Channel: FOX Live Stream: Watch this game on Fubo (Regional restrictions may apply) Over 52.5 – Commanders vs. Ravens Matchup: Washington Commanders at Baltimore Ravens Projected Total: 54.3 points (Bet on this game at BetMGM) Time: 1:00 p.m. ET Date: Oct. 13 TV Channel: CBS Live Stream: Paramount+ | Fubo (Regional restrictions may apply) Under 35.5 – Chargers vs. Broncos Matchup: Los Angeles Chargers at Denver Broncos Projected Total: 31.7 points (Bet on this game at BetMGM) Time: 4:05 p.m. ET Date: Oct. 13 TV Channel: CBS Live Stream: Paramount+ | Fubo (Regional restrictions may apply) Under 49.5 – Cardinals vs. Packers Matchup: Arizona Cardinals at Green Bay Packers Projected Total: 48.5 points (Bet on this game at BetMGM) Time: 1:00 p.m. ET Date: Oct. 13 TV Channel: FOX Live Stream: Watch this game on Fubo (Regional restrictions may apply) Under 52.5 – Lions vs. Cowboys Matchup: Detroit Lions at Dallas Cowboys Projected Total: 47.1 points (Bet on this game at BetMGM) Time: 4:25 p.m. ET Date: Oct. 13 TV Channel: FOX Live Stream: Watch this game on Fubo (Regional restrictions may apply) Catch every NFL touchdown with NFL RedZone on Fubo. Not all offers available in all states, please visit BetMGM for the latest promotions for your area. Must be 21+ to gamble, please wager responsibly. If you or someone you know has a gambling problem, contact 1-800-GAMBLER. The post NFL Week 6 Computer Predictions, Best Bets, Over/Under Picks appeared first on Austin Daily Herald.