EAST LANSING, Mich. (WCMH) -- For the first time this season, Ohio State is on the road. The third-ranked Buckeyes open up their Big Ten schedule against Michigan State at Spartan Stadium. OSU hasn't lost in East Lansing since 1999 and are coming off three-straight decisive victories during the non-conference portion of the regular season, including a 49-14 win over Marshall last week. Meanwhile, Michigan State is 3-1, including a Big Ten road win at Maryland on Sept. 7. The primetime showdown is being streamed exclusively on Peacock. The Buckeyes return home next weekend to host Iowa at 3:30 p.m. Ohio State injury report: DT Tyleik Williams to return for Michigan State game Scroll below for live updates throughout the evening.