COLUMBUS, Ohio (WCMH) – As the stakes are high in Week 5 for Ohio State as it faces its first Big Ten opponent of the season, starting defensive tackle Tyleik Williams is making his return after missing last week's game against Marshall due to an injury. Ohio State will face Michigan State Saturday in East Lansing, Michigan. Kickoff is at 7:30 p.m., with the game being streamed on Peacock. The Spartans will easily be Ohio State’s toughest opponent after the Buckeyes picked up lopsided victories over Akron, Western Michigan and Marshall. Michigan State is coming off a narrow 23-19 loss to Boston College last weekend but already have a conference win, 27-24 over Maryland on the road in Week 2. Ohio State injury report (Week 5 vs. Michigan State) OUT Linebacker Zach Hayes Running Back Rashid Sesay Wide Receiver Reis Stocksdale Running Back Timothy Caffey Through three games, the Buckeyes offense has largely been led on the ground by running backs Quinshon Judkins and TreVeyon Henderson. The two have combined for 543 rushing yards and nine touchdowns, averaging 9.1 yards a carry.